Which symptom is commonly associated with exacerbations of chronic obstructive pulmonary disease (COPD)?

Wheezing is a common symptom associated with exacerbations of chronic obstructive pulmonary disease (COPD) because it occurs due to bronchoconstriction, inflammation, and increased mucus production in the airways. During exacerbations, which can be triggered by infections, air pollution, or other irritants, the airways become more narrowed, making it difficult for air to flow in and out of the lungs. As a result, patients may produce a high-pitched whistling sound during breathing, especially when exhaling.

In contrast, severe headaches and nausea are not typical symptoms of COPD exacerbations. These symptoms can be caused by a variety of other medical issues and are not directly related to the respiratory difficulties experienced by those with COPD. Chest pain may also occur in patients with COPD, but it is not universally present and can be more indicative of other conditions, such as cardiac issues, rather than being a hallmark symptom of a COPD exacerbation.