Potassium has an inverse relationship with which of the following?

Potassium does indeed have an inverse relationship with pH, insulin, and calcium. In the context of acid-base balance, as the pH decreases (becoming more acidic), potassium levels tend to increase because hydrogen ions move into the cells, and potassium ions move out to maintain equilibrium. This phenomenon is especially evident during metabolic acidosis.

Regarding insulin, when insulin is released, it facilitates the uptake of potassium into cells, which can reduce serum potassium levels; thus, high insulin levels can correlate with lower serum potassium levels.

Calcium also plays a role, as elevated calcium levels can actually cause a decrease in serum potassium concentrations due to shifts across the cell membranes.

This complex interaction shows how critical understanding potassium's relationships with these substances is in managing patient care, especially for those with conditions affecting the kidneys, diabetes, or acid-base disorders.